IndraLab

Statements

USP25 activates NFkappaB. 3 / 3
| 1 2
sparser
"We found that the DUB, USP25 xref inhibited IL-17-but not TNF-induced activation of NF-κB in reporter assays in HeLa cells and in 293T cells transfected with IL-17RA and IL-17RC (293T-IL-17RA/C) ( xref and xref )."
23042150
sparser
"The analysis suggested that reconstitution of USP25 almost completely inhibited IL-17-induced activation of NF-κB compared to USP25(C178S) (0.89 v."
23042150
reach
"An additional study has revealed that depletion of USP21 decreases IL33 protein levels and IL33 mediated NF-kappaB p65 promoter activity, indicating USP21 is able to positively regulate the NF-kappaB signaling pathway."
28105162