IndraLab

Statements


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"Heteromeric KCNQ2 and KCNQ3 channels have been proposed to underlie the neuronalM-current, a subthreshold, non-inactivating potassium current which is an important determinant of membrane excitability[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"KCNQ2 and KCNQ3 K+ channel subunits underlie the muscarinic regulated K+ current (I (KM)), a widespread regulator of neuronal excitability."

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"It is suggested that KCNQ2 and KCNQ3 contribute to the formation of the native M-current, a slowly activating and deactivating potassium conductance."

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"Co-expression of KCNQ2 and KCNQ3 leads to a large increase of the potassium current, suggesting that the proteins interact as heterodimers."