IndraLab

Statements


RAC1 is ubiquitinated on K147. 4 / 4
| 4

sparser
"XIAP can promote degradative ubiquitination of Rac1 at Lys147 [ xref ] and cdc42 at Lys166 [ xref ] and cIAP1 can induce ubiquitination of Rac1."

sparser
"In human, IAP s directly ubiquitinate Rac1 at lysine 147 resulting in its proteasomal degradation under CNF1 toxin treatment ( xref )."

sparser
"The ubiquitination of RAC1 at its major ubiquitination site K147, which is the Ub-site regulated in this study, is dependent on the activity of c-Jun N-terminal kinases (MAPK8, MAPK9, MAPK10) ( xref )."

sparser
"Activated Rac1, but not the tumorigenic variant Rac1b, is ubiquitinated on Lys 147 through a JNK-regulated process."