IndraLab
Statements
Recombinase inhibits USP9X. 1 / 1
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"Studies have shown that the constitutive deletion of Fam20B in mice leads to embryonic lethality at E13.5 [ xref ], and that the conditional ablation of Fam20B in the dental epithelium of mice using K14 - Cre recombinase leads to supernumerary incisors, and inactivation of mouse Fam20B by Osr2-Cre recombinase causes chondrosarcoma and postnatal ossification defects in the joint cartilage via the alterations of the WNT, BMP, and PTHrP/IHH signaling pathways [ xref , xref ]."