IndraLab

Statements

TNF activates OTUD7B. 4 / 5
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"Cezanne is induced by TNF‐alpha in cultured cells leading to down‐regulation of NF‐κB signalling through the deubiquitination and inactivation of RIP1, thereby providing a negative feedback loop in pro‐inflammatory signalling (85)."
20073038
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"Our subsequent studies revealed that Cezanne can be induced by TNFα, IL-1 and functions as an inhibitor of NF-κB, thus forming a negative feedback loop in inflammatory cytokine signalling , and a recent report indicated that Cezanne can also influence non-canonical NF-κB activation ."
23564640
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"Given that Cezanne can be modulated by shear stress, TNFα, IL-1 and reactive oxygen species , future studies should address whether these factors influence inflammatory responses to hypoxia-reoxygenation by altering the expression and/or activity of Cezanne."
23564640
reach
"Cezanne is induced by TNF-alpha in cultured cells leading to down-regulation of NF-jB signalling through the deubiquitination and inactivation of RIP1, thereby providing a negative feedback loop in pro-inflammatory signalling (85) ."
20073038