IndraLab

Statements


USP5 deubiquitinates CCND1. 2 / 2
| 2

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"Given that USP5 is a deubiquitinating enzyme (24), we wondered whether USP5 could directly interact with and deubiquitinate CCND1 to stabilize CCND1 protein."

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"Further, we found that USP5 could physically interact with and deubiquitinate CCND1, thereby stabilizing the protein level of CCND1 and prolonging its half-life."