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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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MAP3K5 bound to TXN inhibits MAP3K5. 3 / 3

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"Since thioredoxin is bound to ASK-1 and inhibits the activation of ASK-1 [XREF_BIBR - XREF_BIBR, XREF_BIBR], experiments were carried out to evaluate whether thioredoxin knockdown activates ASK-1 and downstream MAPK signaling pathways in the E47 cells."

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"In resting cells, ASK1 is bound to either thioredoxin or CIB1, two known endogenous inhibitors of ASK1 [26,27]."

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"Since thioredoxin is bound to ASK-1 and inhibits the activation of ASK-1, experiments were carried out to evaluate whether thioredoxin knockdown activates ASK-1 and downstream MAPK signaling pathways in the E47 cells."

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MAP3K5 bound to TXN inhibits MAP3K5. 3 / 3

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