IndraLab

Statements

USP12 deubiquitinates AR. 6 / 6
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reach
"USP12 in the presence of its cofactors Uaf-1 and WDR20 deubiquitinates AR to enhance AR protein stability and transcriptional activity [71] USP12 in complex with Uaf-1 and WDR20 also abrogates phospho[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
30217566
ubibrowser
"The AR is known to be regulated by a number of post-translational modifications and we have recently identified the deubiquitinating enzyme Usp12 as a positive regulator of AR."
26462181
reach
"We determined that Usp12 deubiquitinates the AR resulting in elevated receptor stability and activity."
26462181
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"We have recently reported that AR is deubiquitinated and stabilised by Usp12 resulting in increased transcriptional activity."
25216524
reach
"We find that USP12 deubiquitinates MDM2 and AR, which in turn controls the levels of the TP53 tumour suppressor and AR oncogene in prostate cancer."
29755129
reach
"In this report we demonstrate that Usp12, in complex with Uaf-1 and WDR20, deubiquitinates the AR to enhance receptor stability and transcriptional activity."
24056413