IndraLab

Statements


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"In addition, AF has been associated with rare gain of function mutations in KCNQ1, hERG and KCNJ2 causing the short QT syndrome and sudden death."

sparser
"This is largely due to reduced L-type Ca 2+ current, although rare gain-of-function mutations in KCNQ1 [ xref ], hERG [ xref ], Kir2.1 [ xref ] and KCNE ancillary subunits [ xref ] have also been associated with AF due to increases in channel conductance."