IndraLab

Statements

KCNH7 decreases the amount of ergosterol. 3 / 3
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"Similarly, resistance against amphotericin and echinocandins is rare; however, it does occur if levels of the plasma membrane ergosterol and the cell wall (1,3)-beta-D-glucan are reduced by mutations in the ERG3 and GSC1 genes, respectively [XREF_BIBR]."
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"It has been reported that mutations in the ERG3 gene that reduce the amount of ergosterol causes drug resistance in various fungal strains by stripping the drug of its intended target [66-68]."
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"It has been reported that mutations in the ERG3 gene that reduce the amount of ergosterol causes drug resistance in various fungal strains by stripping the drug of its intended target [XREF_BIBR - XREF_BIBR]."
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