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MTORC1 phosphorylates ASXL1. 22 / 22
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"As we previously found, expression of wild-type UCH-L1 inhibits the mTORC1 phosphorylation of p70 S6 kinase (S6K) and the eIF4E binding protein 1 (4EBP1) and increases the phosphorylation of AKT S473 (Fig. xref a, b)."
31839994
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"Subsequently, mTORC1 induces the phosphorylation of ribosomal protein S6 kinase (S6K) and eukaryotic translation initiation factor 4E-binding protein 1 (4E-BP1)."
28915718
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"Upon activation, mTORC1 directly phosphorylates the eukaryotic translation initiation factor 4E (eIF4E) binding protein 1 (4E-BP1) and S6 kinase 1 (S6K1) to promote protein synthesis [ xref ]."
29375734
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"MTORC1 phosphorylates p70 S6 kinase (S6K1) and eukaryotic initiation factor 4E (eIF4E) binding protein 1 (4E-BP1), and regulates cell growth, proliferation, and survival by integrating hormones, growth factors, nutrients, stressors and energy signals."
20491627
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"MTORC1 phosphorylates p70 S6 kinase (S6K1) and eukaryotic initiation factor 4E (eIF4E) binding protein 1 (4E-BP1), and regulates cell growth, proliferation, survival and motility."
21190521
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"MTORC1 directly phosphorylates the two key translation regulators p70 ribosomal S6 kinase (P70S6K) and eukaryotic initiation factor 4E binding protein 1 (4E-BP1)."
26097872
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"Activated mTORC1 drives the phosphorylation of eukaryotic initiation factor 4E (eIF4E) binding protein 1 (4E-BP1) and ribosomal p70 S6 kinase 1 (S6K1) ( Maiese et al., 2013 )."
29928901
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"MTORC1 phosphorylates both the 70-kDa ribosomal S6 kinase (S6K1) and the translational repressor 4 elongation factor-binding protein 1 (4E-BP1) ( xref )."
22484804
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"When active, mTORC1 phosphorylates the translational regulator eukaryotic translation initiation factor 4E (eIF4E) binding protein 1 (4E-BP1) and S6 kinase 1 (S6K1), which, in turn, promote protein synthesis [ xref , xref ]."
24387336
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"In particular, mTORC1 phosphorylates p70 S6 kinase (S6K) and eukaryotic initiation factor 4E binding protein 1 (4EBP1), thereby regulating translation of proteins that are critical for progression from G1 into S phase [ xref ]."
28238967
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"MTORC1 phosphorylates p70 ribosomal protein S6 kinase (p70 S6K) and eukaryotic initiation factor 4E binding protein 1 (4EBP1), which activates the ribosomal protein S6 (RPS6) and relieves eukaryotic initiation factor 4E (eIF4E), respectively."
28733220
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"Once active, mTORC1 phosphorylates ribosomal protein S6 kinase (p70S6K) and eukaryotic translation initiation factor 4E-binding protein 1 (4EBP1), promoting protein synthesis, including the translation of MYC and HIF1α ( xref )."
29049843
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"MTORC1 phosphorylates and activates the 70 kDa ribosomal S6 kinase (S6K1) and the translational repressor 4 elongation factor binding protein 1 (4E-BP1) [ xref , xref ] to promote cell growth and proliferation."
21128010
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"In its active form, mTORC1 phosphorylates the eukaryotic translation initiation factor 4E (eIF4E) binding protein 1 (4E-BP1) and S6 kinase 1 (S6K1), which, consecutively, induce protein synthesis [ xref ]."
26997506
sparser
"When active, mTORC1 phosphorylates the translational regulators eukaryotic initiation factor 4E (eIF4E) binding protein 1 (4E-BP1) and S6 kinase 1 (S6K1)."
25092520
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"MTORC1 directly phosphorylates the translational regulators eukaryotic translation initiation factor 4E (eIF4E) binding protein 1 (4E-BP1) and S6 kinase 1 (S6K1), which, in turn, promote protein synthesis (reviewed in ( xref ))."
22500797
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"MTORC1 phosphorylates eukaryotic initiation factor 4E-binding protein 1 (4EBP1) and p70-kDa S6 ribosomal protein kinase (p70S6K), promoting cap-dependent mRNA translation, ribosome biogenesis, and polysome assembly ( xref , xref )."
25724525
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"When active, mTORC1 phosphorylates eIF4E Binding Protein 1 (4E-BP1), thus rendering eIF4E free from 4E-BP1 inhibition, and thereby promotes cap-dependent initiation ( xref ; xref ; xref )."
34358439
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"Furthermore, mTORC1 positively regulates phosphorylation of S6K (at the Threonine 389 residue) and eukaryotic initiation factor 4E binding protein 1 (4E-BP1), which together control protein translation ( xref )."
20421047
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"MTORC1 phosphorylates p70 S6 kinase (S6K) and eukaryotic initiation factor 4E (elF4E) binding protein 1 (4E-BP1) and regulates cell growth, proliferation, survival, and motility by integrating growth factors, nutrients, stressors, and energy signals xref , xref ."
22059905
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"While mTORC1 phosphorylates p70S6kinase (S6K) and eukaryotic initiation factor 4E-binding protein 1 (4EBP1) to increase protein synthesis, mTORC2 directly phosphorylates Akt, enhancing its kinase acti[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
29408410
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"MTORC1 phosphorylates S6 kinase, S6 ribosomal protein and eukaryotic translation initiation factor 4E-binding protein 1 (4E-BP1) which together increase protein translation and cell proliferation [ xref , xref - xref ]."
22001078