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EGFR-vIII inhibits USP11. 2 / 2

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"In addition, EGFR-vIII enhanced silencing of the USP11 promoter through the PI3K and AKT-HDAC 1/2 axis."

31993801

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"In addition, EGFR-vIII enhanced silencing of the USP11 promoter through the PI3K/AKT-HDAC1/2 axis.A dynamic balance between histone acetylation and deacetylation is maintained to regulate gene expression appropriately; a disturbance in this balance in cancer though altered gene expression can accelerate cell cycle progression [47]."

31993801

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IndraLab

Statements

EGFR-vIII inhibits USP11. 2 / 2

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