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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

YOD1 leads to the deubiquitination of TRAF6. 1 / 1

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"Another DUB, YOD1 (also called Otud2), inhibits TRAF6 ubiquitination and signaling function via a non-catalytic mechanism that involves binding to the C-terminal TRAF domain of TRAF6 and, thereby, preventing TRAF6 interaction with an activating adaptor protein, p62 (also called Sequestosome-1) (67)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...