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Antagonist inhibits NFKBIA. 1 / 1

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"Therefore, these data suggest that ACE2/Ang-(1-7)/Mas may have a protective effect on LPSinduced apoptosis and inflammation in PMVECs, mainly through inhibition of the JNK pathway.In the present study, we found that ACE2 overexpression significantly inhibited LPS-induced activation of the NF-kB and degradation of IkBa protein, which was strikingly reversed by the Mas receptor antagonist."

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Antagonist inhibits NFKBIA. 1 / 1

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