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USP5 increases the amount of mebendazole. 2 / 2

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"Notably, we found that USP5 mRNA expression was also decreased by mebendazole, suggesting that mebendazole might suppress USP5 transcription."

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"The mechanistic investigation showed that mebendazole not only prevents the interaction between USP5 and c-Maf but also suppresses USP5 transcription, thus inducing c-Maf proteasomal degradation."

31197245

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IndraLab

Statements

USP5 increases the amount of mebendazole. 2 / 2

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