IndraLab

Statements

SHC1 binds USP15. 13 / 13
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sparser
"The interaction between USP15 and p66Shc may be attributed to the deubiquination of p66Shc by USP15."
36163170
sparser
"Thus, USP15 interacts with p66Shc and stabilizes p66Shc expression via its deubiquitinating activity."
36163170
biogrid
No evidence text available
19380743
sparser
"USP15 interacts with p66Shc."
36163170
sparser
"We found that USP15 interacts with p66Shc in the SH2 domain that has been shown to be critical for protein-protein interactions [ xref ]."
36163170
sparser
"Using tandem affinity purification/mass spectrometry (TAP/MS) and co-immunoprecipitation (Co-IP)/MS, we identified the interaction between USP15 and p66Shc."
36163170
sparser
"Specifically, USP15 interacted with the SH2 domain of p66Shc and maintained its stabilization by removing ubiquitin."
36163170
sparser
"As shown in Fig. xref , USP15 and p66Shc efficiently interacted with each other."
36163170
sparser
"Thus, the interaction between USP15 and p66Shc mainly depends on the deubiquitylating activity of USP15."
36163170
sparser
"This study aimed to investigate the molecular mechanism of p66Shc in liver I/R and characterize the interaction between USP15 and p66Shc."
36163170
sparser
"The following study focused on the interaction between USP15 and p66Shc, and the interacting peptides between them were shown in Fig. xref ."
36163170
sparser
"Strikingly, the clinical relevance of USP15 and p66Shc was observed in patients subjected to liver transplantation, indicating a potential interaction between USP15 and p66Shc in liver I/R injury."
36163170
sparser
"Considering the interaction between USP15 and p66Shc as well as the deubiquitinating activity of USP15, USP15 may exert an effect on p66Shc deubiquitination."
36163170