IndraLab

Statements

VCPIP1 activates NSFL1C. 3 / 3
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"The deubiquitinase VCIP135, which is associated with the p97 and p47 complex, removes the ubiquitin moiety and thus allows p97 and p47 to fuse the membranes after mitosis (XREF_FIG) 37."
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"Next, we wanted to ascertain whether VCIP135 contributes to p97 and p47 mediated membrane fusion using an in vitro Golgi reassembly assay."
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"As shown in XREF_FIG G, VCIP135 partially prevented alpha-SNAP binding to GST-syn5DeltaTM, suggesting that VCIP135 directs syntaxin5 to p97 and p47 but not to alpha-SNAP and NSF."
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