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USP4 deubiquitinates TUT1. 5 / 5
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"Since USP4 shares several substrates with USP15, TUT1 is a potent candidate to be deubiquitinated by USP4.In this study, we report that USP4 deubiquitinates TUT1."
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"Therefore, SART3 predominantly binds to USP15, and this complex may exhibit a higher preference for binding to TUT1 compared to USP4 alone.Next, we examined whether USP4 deubiquitinates TUT1."
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"Next, we investigated whether USP4 and USP15 additively deubiquitinate TUT1."
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"Moreover, the co-expression of USP4 and USP15 led to an additive enhancement of deubiquitination, despite the effect not being dramatic ( Fig. 3 B), indicating that both enzymes control TUT1 deubiquit[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Taken together, our data suggest that USP4, similarly to USP15, regulates TUT1 subnuclear localization together with SART3 and increases the U6-snRNA level.In this study, our findings indicate that US[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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