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EIF3F binds MTOR. 23 / 23
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"Importantly, the authors also found that the interaction between mTOR and eIF3f increased at the cell membrane after exercise and this response was enhanced in a fed state (20g protein/ 40 g carbohydrate/ 1 g fat) [172]."
| PMC
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"During the muscle cell growth, eIF3f interacts with mTOR and S6K1 to promote the assembly of the translation initiation complex and is degraded by MAFbx."
23354061
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"Importantly, the authors also found that the interaction between mTOR and eIF3f increased at the cell membrane after exercise and this response was enhanced in a fed state (20g protein / 40 g carbohydrate / 1 g fat) [XREF_BIBR]."
| PMC
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"Interestingly, a protein–carbohydrate beverage post-exercise does not alter MTORC1/eIF3f translocation but increases the interaction between MTOR and eIF3f [ xref ], an association well recognized to drive MTORC1 activation and enhance MTOR target activity [ xref ]."
31195688
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"Inactive S6K1 is bound to eIF3f, and upon amino acid/growth factor/mitogen stimulation, mTOR binds to eIF3f, leading to the phosphorylation and activation of S6K1 (Csibi et al., 2010, Holz and Blenis, 2005)."
23769948
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No evidence text available
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"Indeed, mTOR/raptor complex bound to the scaffold protein eIF3f during muscle hypertrophy, which phosphorylated S6K1 and 's t test) ."
26109581
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"Inactive S6K1 is bound to eIF3f, and upon amino acid/growth factor/mitogen stimulation, mTOR binds to eIF3f, leading to the phosphorylation and activation of S6K1 (Csibi et al., 2010, Holz and Blenis, 2005)."
23769948
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"Interestingly, the interaction between mTOR and eIF3F was greater if resistance exercise was followed by a protein-carbohydrate beverage, compared with the exercise bout in isolation."
30334852
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No evidence text available
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"Interestingly, the magnitude of association between mTOR and eIF3F was ~ 20% greater in the FED group 1h post exercise compared to CON, suggesting that this process is sensitive to post-exercise nutrition."
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"Finally, mTOR activated by Rheb, binds to the scaffold protein eIF3f and exerts its activity on protein synthesis by phosphorylation of the S6K1 protein."
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"Inactive S6K1 is bound to eIF3f, and upon amino acid/growth factor/mitogen stimulation, mTOR binds to eIF3f, leading to the phosphorylation and activation of S6K1 (Csibi et al., 2010; ."
23769948
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"To map the domain of eIF3f that interacts with mTOR, the same panel of deletion mutants of eIF3f was cotransfected with an expression vector encoding HA-tagged mTOR in mouse primary muscle cells."
20126553
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"Inactive S6K1 is bound to eIF3f, and upon amino acid/growth factor/mitogen stimulation, mTOR binds to eIF3f, leading to the phosphorylation and activation of S6K1 ( xref , xref )."
23769948
sparser
"Importantly, the authors also found that the interaction between mTOR and eIF3f increased at the cell membrane after exercise and this response was enhanced in a fed state (20g protein/ 40 g carbohydrate/ 1 g fat) [ xref ]."
| PMC
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"MTOR interacts with the C-terminal domain of eIF3f, a region recently shown to be critical for proper eIF3f activity in skeletal muscle xref ."
20126553
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"Indeed, mTOR/raptor complex bound to the scaffold protein eIF3f during muscle hypertrophy, which phosphorylated S6K1 and regulated downstream effectors of mTOR (51)."
26109581
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No evidence text available
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"Inactive S6K1 is bound to eIF3f, and upon amino acid and growth factor and mitogen stimulation, mTOR binds to eIF3f, leading to the phosphorylation and activation of S6K1."
23769948
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"Indeed association of eIF3f with mTOR and its activation is correlated with S6K1 activation and its respective dissociation from eIF3f."
20126553
sparser
"This reduction in mammalian target of rapamycin (mTOR) kinase activity was associated with reduced eIF3f and binding of both Raptor and eIF4G to eIF3."
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biogrid
No evidence text available
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