IndraLab

Statements

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"For example, USP47 overexpression accelerated ovarian cancer cell development, whereas USP47 knockdown inhibited gastric cancer cell proliferation."
33576460
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"Specifically, we demonstrate that USP47 is highly expressed in primary CML cells and promotes cell proliferation, while Usp47 knockout significantly prolongs the survival of BCR-ABL and BCR-ABL T315I -induced CML mice by reducing leukemia stem and progenitor cells."
33397955
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"Finally , we show that depletion of USP47 induces p53 and therefore inhibits cell proliferation , colony formation , and tumor progression in cancer cell lines and a mouse xenograft model ."
32370049
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"Functional analysis shows that USP47 knockdown represses proliferation of CML cells sensitive or resistant to imatinib in vitro and in vivo."
33397955
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"Ubiquitin specific peptidase 47 promotes proliferation of lung squamous cell carcinoma."
35254655
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"Functional experimental results showed that USP47 promoted the cell proliferation in vitro and tumor growth in vivo ."
35141006
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"Finally , we show that depletion of USP47 induces p53 and therefore inhibits cell proliferation , colony formation , and tumor progression in cancer cell lines and a mouse xenograft model ."
32370049
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"USP47 knockdown inhibits proliferation of CML cells."
33397955
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"USP47 silencing reduces proliferation and migration of colorectal cancer cells and suppresses the self-renewal of CCSCs by downregulating the expression of cancer stem cell markers, including CD44, CD133, CD166, OCT4 and NANOG."
34030041
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"Silencing Usp47 inhibits BCR-ABL T315I -induced CML and proliferation of KBM T315I in a xenograft mouse model."
33397955
eidos
"Finally , we provide evidence that USP47 has oncogenic potential , and depletion of USP47 induces p53 by regulation of RPS2 and , therefore , inhibits cell proliferation , colony formation , and tumor progression in cancer cell lines and a mouse xenograft model in a p53-dependent manner ."
32370049
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"USP47 functions as a DUB for YAP in colorectal cancer, USP47 elevation leads to stabilization of YAP and promotes colorectal cancer cell proliferation XREF_BIBR."
33613102