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USP8 deubiquitinates SNCA. 2 / 2

2 |

"In addition, this study identifies USP8 as one of the best markers of Lewy bodies in human pigmented neurons in sporadic cases of Parkinson’s disease and demonstrates the ability of USP8 to hydrolyze K63-linked ubiquitin chains from α-synuclein in vitro"

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"Another deubiquitinase, USP8, removes K63-linked ubiquitin chains of α-synuclein and prevents its lysosomal degradation."

27444016

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IndraLab

Statements

USP8 deubiquitinates SNCA. 2 / 2

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