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MYSM1 inhibits CLPS. 1 / 1
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"We further establish that PUMA, but not p21, is an important mediator of the p53 driven hematopoietic dysfunction in Mysm1 deficiency, with Mysm1 -/- Puma -/- mice showing full rescue of MPP4 cell viability, partial rescue of HSC functions, but persistent depletion of CLPs and lymphopenia."