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USP15 binds BMP receptors. 2 / 2

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"It was shown that USP15 interacts with type I BMP receptors, including ALK3, co-localises with ALK3 at the membrane and deubiquitylates ALK3, thereby countering the inhibition of the BMP pathway caused by SMAD6 XREF_BIBR."

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"Moreover, we show that USP15 interacts with other type I BMP receptors ALK2 and ALK6, as well as TGFbeta receptor ALK5."

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IndraLab

Statements

USP15 binds BMP receptors. 2 / 2

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