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USP15 decreases the amount of p53-R175H. 2 / 2

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"Interestingly, knockdown of USP15 in both TYK-Nu and TOV112D cells caused p53-R175H levels to decrease."

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"These results are consistent with our previous observations that the effect of MCB-613 on p53-R175H is post-translational, and that depletion of USP15 causes decreases in p53-R175H levels in TYK-Nu cells, but not p53-R273H in OVCA420 cells."

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IndraLab

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USP15 decreases the amount of p53-R175H. 2 / 2

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