IndraLab

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"ChIP-qPCR of the promoters of Sox2, Nanog, Oct4, and Cbx7 in Usp26 differentiated ESCs on day 6 revealed binding of USP26, CBX4, CBX6, H2A-ubi1, and H3K27me3 to the Sox2, Nanog, and Cbx7 promoters, suggesting that promoter binding of these components led to a decrease in pluripotency gene expression."

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"Similarly, during RA induced ESC differentiation, USP26, CBX4, CBX6, H2A-ubi1, and H3K27me3 also bound to the Sox2, Nanog, and Cbx7 promoters."