IndraLab

Statements



sparser
"We noted that A20 significantly inhibited poly(I:C)-induced cytokine production, and this effect was related to the inhibition of NF-κB signaling."

eidos
"Downstream of TLR activation , Quercetin supplement decreased cytokine production by regulating NF-kB activation and possibly modulating A20 expression , in response to oral bacteria and TLR agonist challenge ."

reach
"We hypothesized that lower levels of TNFAIP3 contributes to excessive cytokine production in response to inflammatory stimuli in axial spondyloarthritis (AxSpA)."

sparser
"Porphyromonas gingivalis (P. gingivalis) , one of the keystone periodontal bacteria, can activate NF-κB signaling in macrophages and induce A20 expression in vivo when injected intraperitoneal cavity of mice and therefore it is included as a model oral bacteria in in vitro assays. ( xref ) Our results revealed that A20 inhibits pro-inflammatory cytokine production both in human and mouse macrophages infected with P. gingivalis through its effect on NF-κB signaling."

eidos
"Downstream of TLR activation , Quercetin supplement decreased cytokine production by regulating NF-kappaB activation and possibly modulating A20 expression , in response to oral bacteria and TLR agonist challenge ."

reach
"Given the relationship we observed between elevated TNFAIP3 and decreased TNF-alpha, the lower levels of TNFAIP3 in AxSpA subjects may contribute to excessive cytokine production in response to PRR agonists."