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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

IGF1 binds IGF1R, IRS1, and PIK3CA. 2 / 2

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"These findings suggest that IGF-I-induced association of p110α with IGF-IR and IRS-1 is enhanced when p110β levels are reduced."

19834495

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"Our results suggest that p110β deficiency leads to increased Akt activation through two separate mechanisms: First, reduced p110β levels enhance the IGF-I-induced association of p110α with IGF-IR and IRS-1."

19834495

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...