IndraLab

Statements

UCHL5 activates HYCC1. 9 / 9
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"We overexpressed UCHL5 while inhibiting β-catenin or adding a β-catenin inhibitor to further determine if UCHL5 accelerates HCC development by stimulating the Wnt/β-catenin pathway."
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"Our previous results showed that UCHL5 promoted the glycolysis of HCC cells."
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"UCHL5 promotes the proliferation and metastasis of HCC cells in vivo."
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"UCHL5 promotes the growth and metastasis of HCC cells in vitro."
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"The results show that the knockdown of UCHL5 significantly inhibited HCC cell metastasis."
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"These findings demonstrate that UCHL5 promotes the in vitro proliferation and metastasis of HCC cells."
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"UCHL5 promotes glycolysis of HCC cells."
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"The final intuitive effect is that high UCHL5 expression promotes glycolysis of HCC cells to provide energy for the proliferation and metastasis of HCC cells, this is unreported in earlier investigations."
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"UCHL5 promotes HCC progression through beta-catenin."
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