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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

BetA inhibits KCNMA1. 1 / 1

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reach

"Thus, the differential efficacy of beta- versus alpha-hydroxyl-containing monohydroxysterols to reduce BK channel activity could also be attributed to differences in the bilayer lateral stress that is generated by sterol incorporation into the phospholipid bilayers : the different spatial characteristic of the C3 hydroxyl imposed by the beta versus alpha configuration modify sterol overall molecular volume (area per molecule), a likely contributor to the bilayer lateral stress that results from sterol insertion."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...