IndraLab

Statements


EGF leads to the phosphorylation of TSC2. 6 / 6
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sparser
"EGF induced a rapid phosphorylation of Akt, tuberin, p70S6K and 4E-BP1 ( xref )."

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"EGF induced a rapid phosphorylation of Akt, tuberin, p70S6K and 4E-BP1 (XREF_FIG)."

sparser
"Either U0126 or wortmannin (a PI3K inhibitor) could suppress TSC2 phosphorylation by EGF, while treatment with both inhibitors led to a further reduction ( Figure 1 B), suggesting that upon mitogenic [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

reach
"Moreover, they were able to inhibit the epidermal growth factor induced Akt activation and tuberin phosphorylation."

sparser
"This subcellular redistribution of active RSK1 is manifested by increased phosphorylation of its cytosolic substrates tuberous sclerosis complex 2 and BAD by epidermal growth factor along with decreased cellular apoptosis."

reach
"Epidermal growth factor can similarly induce tuberin phosphorylation and degradation via a PI3K and Akt pathway in PC-12 cells, but these responses were insensitive to pertussis toxin treatment."