IndraLab

Statements


RES inhibits NLRP3. 5 / 5
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"RES, by activation of sirtuin-1 (Sirt-1) signaling, can inhibit nuclear factor kappa beta (NF-kappab) and then NLRP3 inflammasome activity."

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"In addition , Ang ( 1-7 ) and RES significantly decreased the levels of NLRP3 , which were increased by AngII and A779 ."

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"Moreover, RES treatment attenuated NLRP3 inflammasome protein activation at 48 hours after ischemia in DM rats while concomitantly reducing the expression of caspase-1 and release of IL-1beta and IL-18."

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"In this study, we showed that RES by its anti-inflammatory properties decreases NLRP3 inflammasome activity in the testis tissue."

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"Besides, RES alleviated PM 2.5 -induced cytotoxicity, inhibited autophagic process and NLRP3 inflammasome activity and decreased IL-1beta production in BEAS-2B cells."