IndraLab

Statements

CYLD inhibits TOPFlash reporter. 3 / 3
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"CYLD knockdown did not enhance basal levels of TOPFlash reporter activity in HEK293T cells, but strongly increased the response to Wnt3a."
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"Furthermore, overexpression of CYLD reduced TOPFlash reporter activity."
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"TOPFlash reporter activity initiated by enhanced expression of the upstream components, Fz5 or Dvl1, was substantially increased by CYLD knockdown, whereas signaling induced by ectopically enhanced ex[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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