IndraLab

Statements


MAP2K1 phosphorylates MAPK1 on T185. 6 / 11
3 1 1 | 3 3

reach
"For example, evidence supporting the specific Statement, “MAP2K1 phosphorylates MAPK1 on T185,” also supports the more generic Statement, “MEK phosphorylates ERK."

reach
"MEK1 and MEK2 phosphorylate ERK1 and ERK2 on T183 and Y185 residues within the TPY motif (Crews et al., 1992b; Seger et al., 1992; Zheng & Guan, 1993b)."

sparser
"MEK1 and MEK2 phosphorylate ERK1 and ERK2 on T183 and Y185 residues within the TPY motif ."

reach
"As an example of text being converted into an executable model, consider the sentence " MEK1 phosphorylates ERK2 at threonine 185 and tyrosine 187 "."

sparser
"We used a mass spectrometry-based analysis of the undigested or tryptically digested protein to establish that MKK1 exclusively phosphorylates His 6 -ERK2 on Thr-183 and Tyr-185 within the activation loop."

sparser
"For example, evidence supporting the specific Statement, “MAP2K1 phosphorylates MAPK1 on T185,” also supports the more generic Statement, “MEK phosphorylates ERK.” Combining these refining mentions improved precision and recall: the AUPRC of the Random Forest model increased from 0.893 to 0.913 when using only mention counts (Table  xref , row 2 vs. 17), and from 0.932 to 0.937 when using all features (Table  xref , row 9 vs. 24)."