IndraLab

Statements


USP15 deubiquitinates SQSTM1. 4 / 6
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reach
"USP15 and USP17 promote lysosomal exocytosis of lysosomal proteins, including cathepsin D and LGMN, by deubiquitinating p62."

reach
"Similarly, USP15 can also deubiquitinate p62, opposing RFN26 and allowing vesicle release into the cell’s periphery (35)."

reach
"At one point, endosomes leave the cloud, which involves the deubiquitination of SQSTM1 and p62 by the deubiquitinating enzyme USP15, and start their fast bidirectional microtubule based journey in the periphery along microtubules and finally the cortical actin cytoskeleton before reaching the cell surface."

reach
"At one point, endosomes leave the cloud, which involves the deubiquitination of SQSTM1 and p62 by the deubiquitinating enzyme USP15, and start their fast bidirectional microtubule based journey in the periphery along microtubules and finally the cortical actin cytoskeleton before reaching the cell surface."