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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

OTULIN binds Replicase polyprotein 1a. 1 / 1

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sparser

"OTULIN is upregulated in a PRRSV infection model and interacts with the PRRSV non-structural protein 11 (Nsp11) to decrease Ub levels on NEMO and to block NF-κB activation and IFN-regulatory transcription factor 3 (IRF3)-mediated type-I IFN production [ xref ]."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...