IndraLab

Statements

reach
"To investigate the molecular mechanism by which USP14 promoted proliferation and invasion in ESCC cells, we examined the effects of USP14 on the activation of the Wnt and beta-catenin signaling pathway."
27629392
reach
"Overexpression of USP14 could enhance proliferation, prevent apoptosis and promote invasion and migration of PDAC cells."
33394290
reach
"Furthermore, administration of the IU1-47 small molecule or siRNA inhibition of USP14 was demonstrated to significantly decrease lung cell proliferation, migration, and invasion."
35069211
reach
"In addition, IU1, a small-molecule inhibitor of USP14, accelerated the degradation of a subset of proteasome substrates and suppressed cell proliferation, migration, and invasion in lung cancer and cervical cancer."
33791305
eidos
"USP14 depletion or its specific inhibitor IU1 treatment decreased cell proliferation , invasion , migration , and Vascular Mimicry ( VM ) formation even under hypoxia conditions in HCC cell lines ."
34420039
reach
"Genetic or pharmaceutical inhibition of USP14 has been shown to significantly decrease the proliferation, migration, and invasion of lung cancer cells."
35069211