IndraLab

Statements


EHMT1 methylates TP53. 6 / 6
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sparser
"G9a and Glp specifically methylate p53 at Lys(373), resulting mainly in dimethylation."

reach
"For instance, SETD7, G9A, GLP and SETD8 methylate p53 (as well as other non histone substrates) 2."

sparser
"For example, there is convincing evidence that G9a and GLP physiologically methylate LIG1, p53, WIZ, Reptin, ACINUS, CDYL1 and other substrates (see xref ), with LIG1 being a particularly high-affinity substrate xref ."

sparser
"For example, there is convincing evidence that G9a and GLP physiologically methylate LIG1, p53, WIZ, Reptin, ACINUS, CDYL1 and other substrates (see xref ), with LIG1 being a particularly high-affinity substrate xref ."

sparser
"For instance, G9a and GLP can methylate the tumor suppressor p53 [ xref ]."

reach
"XREF_BIBR, XREF_BIBR Some nonhistone targets, similar to histones, can be modified by multiple PMTs (e.g. site specific methylations of the tumor suppressor p53 by SET7/9, SET8, G9a, GLP1, SMYD2 and PRMT5), XREF_BIBR, XREF_BIBR, XREF_BIBR, XREF_BIBR, XREF_BIBR which may resemble the histone-code scenario for epigenetic regulation."