IndraLab

Statements


IGF1R leads to the phosphorylation of SRC. 4 / 4
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rlimsp
"These findings revealed the ability of IGF-1R to phosphorylate Src."

sparser
"Activated IGFR in turn phosphorylates the insulin receptor substrate 1–4 and src- and collagen-homology adaptor proteins, which can trigger multiple downstream signal transduction pathways ."

reach
"In addition, C-ANP 4-23 treatment also attenuated the enhanced expression of AT1 receptor, Gqalpha, PLCbeta1, Nox4, and p47 phox proteins, the enhanced activation of EGFR, PDGFR, IGF-1R, enhanced phosphorylation of ERK1/2/AKT and c-Src in VSMC from SHR."

rlimsp
"An in vitro kinase assay showed that IGF-1R immunoprecipitated from A549 cells phosphorylated Src (Fig. 2k; Additional file 6: Figure S5F)."