IndraLab

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MINDY4 activates cell growth. 9 / 9
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"FAM188B knockdown induced the inhibition of cell growth along with the downregulation of mRNA and protein levels of FOXM1 ."
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"In addition, FAM188B knockdown decreased cell growth in the 3D culture condition, which mimics in vivo conditions (XREF_FIG E)."
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"FAM188B knockdown induced cell growth inhibition due to an increase in apoptosis in colon cancer cell lines."
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"FAM188B was downregulated by si-RNA targeting FAM188B ( Figure 1B ) , and cell growth was significantly inhibited by FAM188B knockdown as assessed by 3 - ( 4,5 - dimethylthiazol-2-yl ) -5 - ( 3-carboxyme-thoxyphenyl ) -2 - ( 4-sulfophenyl ) -2 H-tetrazolium ( MTS ) assay in A549 , H1299 , and H1975 cells ( Figure 1C ) ."
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"FAM188B knockdown induced the inhibition of cell growth along with the downregulation of mRNA and protein levels of FOXM1."
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"FAM188B was downregulated by si-RNA targeting FAM188B (XREF_FIG B), and cell growth was significantly inhibited by FAM188B knockdown as assessed by 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxyme-thoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium (MTS) assay in A549, H1299, and H1975 cells (XREF_FIG C)."
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"In addition , FAM188B knockdown decreased cell growth in the 3D culture condition , which mimics in vivo conditions ( Figure 4E ) ."
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"Knockdown of FAM188B stimulated cell growth inhibition, through an increase of apoptosis in colon cancer cell lines.46 Proteomic analysis of FAM188B immunocomplexes identified p53 and USP7 as interaction partners of FAM188B."
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"Knockdown of FAM188B stimulated cell growth inhibition , through an increase of apoptosis in colon cancer cell lines.46 Proteomic analysis of FAM188B immunocomplexes identified p53 and USP7 as interaction partners of FAM188B ."
35005106