IndraLab

Statements

PTEN inhibits phosphorylated MTOR. 6 / 6
| 6
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"In human hepatocellular carcinoma, PTEN loss and overexpression of p-AKT and p-mTOR were correlated with TNM stage, vascular invasion, intrahepatic metastasis, tumor grade, and Ki-67 high expression, and PTEN loss was associated with p-AKT, p-mTOR, and MMP-9 overexpression [XREF_BIBR]."
29384143
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"Western blot assay further demonstrated that Scutellarin administration significantly enhanced the expression of PTEN but downregulated p-AKT and p-mTOR in dissected tumor tissues."
30257368
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"In HCC, PTEN loss and overexpression of p-AKT and p-mTOR were associated with tumor grade, intrahepatic metastasis, vascular invasion, TNM stage and high Ki-67 labeling index (P < 0.05)."
19208038
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"We found that MTE treatment increased PTEN level and decreased p-AKT and AKT and p-mTOR and m-TOR."
27756877
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"The overexpression of miR-486 inhibited the expression of PTEN both at the mRNA and protein levels and thus increased the levels of AKT, phosphorylated AKT, mTOR and phosphorylated mTOR."
25738494
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"Western blotting indicated harmine significantly promoted E-cadherin and PTEN expression, while suppressed N-cadherin, vimentin, PI3K, p-mTOR, and AKT levels."
36656035