IndraLab

Statements

OTULIN binds PUB. 3 / 3
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reach
"52 Interestingly, Otulin binds to the PUB (N-terminal peptide : N-glycanase and UBA- or UBX containing protein) domain of HOIP, while CYLD is also recruited to the PUB domain of HOIP, but indirectly via the protein SPATA2 (spermatogenesis associated protein 2)."
28475177
reach
"LUBAC activity is counterbalanced by the Met1 specific deubiquitinase (DUB) OTULIN, which binds to the catalytic subunit HOIP via interactions between the HOIP peptide : N-glycanase and UBA- or UBX containing proteins (PUB) domain and a PUB interacting motif (PIM) in OTULIN."
26997266
reach
"Mass spectrometry and biochemical analysis showed that OTULIN binds to the HOIP PUB (peptide : N-glycanase and UBA- or UBX containing proteins) domain [XREF_BIBR, XREF_BIBR]."
27913667