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USP15 deubiquitinates FHL1. 3 / 3
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"As we found that SLIM1 was detected in poly-ubiquitinated forms, as well as a non ubiquitinated form, when SLIM1 and Ub were co-expressed in the presence of the proteasome inhibitor MG-132 in HEK293T [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"We found a novel protein protein interaction between ubiquitin specific protease 15 (USP15) and skeletal muscle LIM protein 1 (SLIM1) : USP15 and SLIM1 directly bound under cell-free conditions and co-immunoprecipitated from the lysates of the cells, where they were co-expressed; and USP15 deubiquitinated SLIM1, resulting in the increase of protein levels of SLIM1."

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"In the present study, we have shown that USP15 interacts with SLIM1 and deubiquitinates SLIM1, leading to the stabilization of SLIM1."