IndraLab

Statements



reach
"Significant suppression of STAT1 phosphorylation at Tyr701 was responsible for Type I IFN antagonism of JEV NS5 proteins, in agreement with prior studies: WNV and TBEV NS5 proteins suppressing tyrosine phosphorylation of STAT1 and DEN NS5 protein suppressing tyrosine phosphorylation of STAT2, blocking formation of STAT1/STAT1 homo-or heterodimers in Type I IFN-induced JAK/STAT signaling pathway [8, [10] [11] [12] [13] 35] ."