IndraLab

Statements

COPS5 activates CUL1. 5 / 5
| 5
reach
"We found these CSN6 mutants compromised their competitive activity in preventing binding between CSN5 and Cullin-1 when compared with wt CSN6; therefore, their capacity to interfere with endogenous CSN5 mediated deneddylation of Cullin-1 was also altered (XREF_FIG)."
25395170
reach
"The BYSMV P6 protein interacted with the constitutive photomorphogenesis 9 signalosome subunit 5 (CSN5) of barley plants in vivo and in vitro, and negatively affected CSN5-mediated deRUBylation of cullin1 (CUL1)."
35771641
reach
"The perdurance of the pre-recombinant wild type CSN5 or Nedd8 proteins in post-recombinant mosaic clones for CSN5 or Nedd8 mutations in some cases could allow neurons to successfully execute the Cullin1 mediated earlier program and pass the presumable threshold."
19855832
reach
"Subsequently, UCHL3 mediated upregulation of COPS5 promotes Cullin1 deneddylation."
28583475
reach
"Here we show that MsrA interacts with Jab1 and consequently, the Jab1 deneddylase activity (removal of Nedd8) is enhanced, causing an increased deneddylation of Cul-1."
32456285