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MINDY3 inhibits CDK2. 1 / 1
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"In summary (XREF_FIG), we have shown that (a) CARP is downregulated in stomach cancer tissues; (b) CARP functioned as a tumor suppressor by inducing apoptosis, and inhibiting proliferation, migration and adhesion; (c) CARP might cause G1 arrest by promoting p27 and p21 nuclei location, and inhibits cyclin-E and CDK2 activities; (d) rs2297882 in the CARP Kozak sequence is associated with the downregulation of CARP expression and with the susceptibility to stomach cancer."