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Okadaic acid activates KCNQ1. 1 / 1
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"As we have previously reported, XREF_BIBR dialysis of patch clamped Chinese hamster ovary (CHO) cells co-expressing wild type KCNE1, KCNQ1, and Yotiao with cAMP (0.2 mM) and OA (0.2 muM) increases the activity of KCNE1 and KCNQ1 channels that can be quantified by measuring the amplitude of deactivating current tails (after +100 mV test pulses : -cAMP/OA 72.0 +/- 8.7 pA/pF, n = 10; cAMP/OA 133.7 +/- 10.8 pA/pF, n = 10; p < 0.05) (XREF_FIG)."