A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

IndraLab

Statements

databases
phosphosite cbn pc11 biopax bel_lc signor biogrid tas lincs_drug hprd trrust | geneways tees isi trips rlimsp medscan sparser reach
reading

EGF binds EGFR, ERBB4, and EREG. 1 / 1
| 1
sparser
"Each member has distinct binding affinities to different ligands that allows the classification of ligands into three groups: in the first group, EGF, transforming growth factor- α (TGF- α ) and amphiregulin (AREG) specifically bind to EGFR; in the second group, betacellulin, heparin-binding EGF (HB-EGF) and epiregulin bind to both EGFR and ERBB4; the third class include neuregulins (NRGs) that bind to either only ERBB4 (NRG3 and NRG4) or both ERBB3 and ERBB4 (NRG1 and NRG2)."