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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

SMAD4 leads to the deubiquitination of USP9X. 1 / 1

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"A mechanistic explanation for this correlation is provided by the upstream network analysis of the USP9 knockdown transcriptome, exploiting existing molecular interaction data and identifying a regulatory relation between USP9 and MAPT via the USP9 deubiquitination target SMAD4 and the MAPT transcription repressor BACH1, whose transcription is in turn repressed by SMAD4."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...