IndraLab

Statements

Zinc atom inhibits CHUK. 2 / 2
| 2
sparser
"To understand whether zinc selectively inhibits IKKα and/or IKKβ, we exposed IKKβ (−/−) mouse embryonic fibroblast (MEFs) to IL-1β and evaluated NF-κB-mediated function."
23403290
sparser
"Although recombinant IKKα was inhibited by zinc, IKKβ (−/−) MEFs that contain IKKα did not exhibit zinc-mediated inhibition, indicating that the primary effect of zinc occurs directly through inhibition of IKKβ and/or IKKβ-related kinase complex formation."
23403290