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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Ubiquitin activates USP11. 2 / 2

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"However, USP11 FL features a ' burst ' phase (XREF_SUPPLEMENTARY), indicating that, in contrast to USP4 FL and USP15 FL, slow ubiquitin off-rates limit USP11 activity but the DUSP-Ubl domain is not able to promote ubiquitin release or is not efficient in doing so, in agreement with a recent publication XREF_BIBR."

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"Furthermore, the ubiquitin levels of eIF4B were noted to be minimally enhanced in TMD8 cells overexpressing USP11 and treated with C75 compared to either GFP infected or USP11 CS infected corresponding treated cells."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...